![]() ![]() O A is characterized as “hand, foot, and mouth” disease (red vesicular rashes and sores, respectively), aseptic meningitis, pharyngitis, and the common cold Transmission via fecal-oral route – most common during summer months O Virus targets the anterior horn of the spinal cord and replicates in the tonsils and ileal Peyer’s patches every two to three weeksĬoxsackievirus (picornavirus – enterovirus) – “Coxsackie Cockatoos” Treatment via Salk (IgG) vaccine or Sabin (IgM and IgG) – the latter confers group immunity with person-to-person contact Disease includes poliomyelitis (flaccid asymmetric paralysis, decreased DTRs and respiratory insufficiency, muscle atrophy, and aseptic meningitis) Poliovirus (picornavirus – enterovirus) – “Flamingo Breeding Pool” O Wheel-shaped appearance under the microscope O Virulence factor is the NSP4 enterotoxin, which increases chloride permeability Treatment via oral rehydration therapy and live attenuated vaccine – vaccine may induce intussusception (ileum to cecum) due enlarged Peyer’s patches Disease includes watery diarrhea and gastroenteritis – #1 cause of infant gastritis Transmission via fecal-oral route – common to daycares and kindergarten, especially in the winter months ![]() Rotavirus (reovirus) – “A Race on the Rio” ![]()
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